P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 S 0 19 19 0.986 0.789 View mutations
402 T 7 12 19 0.605 0.602 View mutations
403 E 4 15 19 0.798 0.703 View mutations
404 E 0 19 19 1.000 0.903 View mutations
405 G 9 10 19 0.523 0.522 View mutations
406 A 19 0 19 0.000 0.152 View mutations
407 R 17 2 19 0.175 0.302 View mutations
408 L 2 17 19 0.878 0.807 View mutations
409 E 15 4 19 0.196 0.301 View mutations
410 K 15 4 19 0.242 0.393 View mutations
411 A 1 18 19 0.919 0.803 View mutations
412 K 0 19 19 1.000 0.713 View mutations
413 N 0 19 19 1.000 0.706 View mutations
414 A 4 15 19 0.798 0.687 View mutations
415 V 13 6 19 0.291 0.444 View mutations
416 V 1 18 19 0.948 0.679 View mutations
417 K 16 3 19 0.187 0.443 View mutations
418 I 5 14 19 0.725 0.534 View mutations
419 P 5 14 19 0.755 0.537 View mutations
420 E 3 16 19 0.796 0.517 View mutations
421 E 19 0 19 0.011 0.401 View mutations
422 T 19 0 19 0.019 0.432 View mutations
423 E 5 14 19 0.689 0.426 View mutations
424 E 12 7 19 0.338 0.421 View mutations
425 P 19 0 19 0.002 0.532 View mutations