P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 L 15 4 19 0.215 0.405 View mutations
127 A 1 18 19 0.874 0.607 View mutations
128 N 7 12 19 0.662 0.444 View mutations
129 E 18 1 19 0.056 0.431 View mutations
130 Q 4 15 19 0.814 0.532 View mutations
131 I 3 16 19 0.839 0.552 View mutations
132 Q 15 4 19 0.211 0.520 View mutations
133 K 19 0 19 0.002 0.582 View mutations
134 A 19 0 19 0.008 0.528 View mutations
135 G 19 0 19 0.005 0.519 View mutations
136 G 19 0 19 0.052 0.561 View mutations
137 L 17 2 19 0.122 0.487 View mutations
138 K 18 1 19 0.050 0.466 View mutations
139 T 17 2 19 0.138 0.384 View mutations
140 S 7 12 19 0.574 0.539 View mutations
141 S 9 10 19 0.504 0.507 View mutations
142 I 19 0 19 0.001 0.252 View mutations
143 I 19 0 19 0.000 0.274 View mutations
144 I 4 15 19 0.735 0.655 View mutations
145 A 14 5 19 0.318 0.398 View mutations
146 L 13 6 19 0.307 0.375 View mutations
147 T 1 18 19 0.956 0.792 View mutations
148 D 19 0 19 0.000 0.246 View mutations
149 G 7 12 19 0.703 0.566 View mutations
150 K 19 0 19 0.017 0.331 View mutations