P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 E 19 0 19 0.003 0.666 View mutations
27 P 19 0 19 0.001 0.618 View mutations
28 C 0 19 19 1.000 0.383 View mutations
29 F 18 1 19 0.056 0.700 View mutations
30 R 18 1 19 0.059 0.682 View mutations
31 E 18 1 19 0.050 0.658 View mutations
32 E 19 0 19 0.038 0.646 View mutations
33 N 7 12 19 0.587 0.417 View mutations
34 A 19 0 19 0.035 0.700 View mutations
35 N 17 2 19 0.174 0.585 View mutations
36 F 19 0 19 0.063 0.478 View mutations
37 N 19 0 19 0.036 0.456 View mutations
38 K 5 14 19 0.776 0.414 View mutations
39 I 7 12 19 0.646 0.423 View mutations
40 F 6 13 19 0.761 0.422 View mutations
41 L 0 19 19 0.992 0.441 View mutations
42 P 0 19 19 0.981 0.494 View mutations
43 T 19 0 19 0.001 0.456 View mutations
44 I 1 18 19 0.931 0.466 View mutations
45 Y 1 18 19 0.948 0.517 View mutations
46 S 9 10 19 0.478 0.432 View mutations
47 I 6 13 19 0.702 0.446 View mutations
48 I 0 19 19 0.987 0.548 View mutations
49 F 1 18 19 0.921 0.507 View mutations
50 L 1 18 19 0.930 0.409 View mutations