P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 Y 0 19 19 1.000 0.643 View mutations
77 R 0 19 19 1.000 0.632 View mutations
78 L 0 19 19 1.000 0.751 View mutations
79 H 0 19 19 1.000 0.761 View mutations
80 L 0 19 19 1.000 0.879 View mutations
81 S 0 19 19 1.000 0.858 View mutations
82 V 1 18 19 0.967 0.749 View mutations
83 A 0 19 19 1.000 0.868 View mutations
84 D 0 19 19 0.999 0.806 View mutations
85 L 0 19 19 0.992 0.772 View mutations
86 L 2 17 19 0.880 0.712 View mutations
87 F 1 18 19 0.963 0.709 View mutations
88 V 3 16 19 0.725 0.661 View mutations
89 I 6 13 19 0.659 0.565 View mutations
90 T 8 11 19 0.562 0.529 View mutations
91 L 1 18 19 0.917 0.752 View mutations
92 P 4 15 19 0.807 0.631 View mutations
93 F 0 19 19 0.968 0.722 View mutations
94 W 1 18 19 0.951 0.593 View mutations
95 A 1 18 19 0.935 0.593 View mutations
96 V 3 16 19 0.872 0.546 View mutations
97 D 6 13 19 0.642 0.506 View mutations
98 A 17 2 19 0.109 0.384 View mutations
99 V 12 7 19 0.450 0.432 View mutations
100 A 10 9 19 0.441 0.457 View mutations