P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 T 2 17 19 0.889 0.535 View mutations
52 G 0 19 19 1.000 0.655 View mutations
53 I 0 19 19 0.955 0.508 View mutations
54 V 5 14 19 0.763 0.456 View mutations
55 G 3 16 19 0.864 0.629 View mutations
56 N 1 18 19 0.888 0.661 View mutations
57 G 0 19 19 1.000 0.520 View mutations
58 L 4 15 19 0.810 0.577 View mutations
59 V 0 19 19 0.978 0.701 View mutations
60 I 1 18 19 0.947 0.552 View mutations
61 L 2 17 19 0.887 0.408 View mutations
62 V 0 19 19 1.000 0.586 View mutations
63 M 2 17 19 0.903 0.555 View mutations
64 G 1 18 19 0.948 0.593 View mutations
65 Y 2 17 19 0.851 0.433 View mutations
66 Q 2 17 19 0.902 0.525 View mutations
67 K 4 15 19 0.782 0.460 View mutations
68 K 1 18 19 0.905 0.460 View mutations
69 L 19 0 19 0.020 0.467 View mutations
70 R 5 14 19 0.724 0.458 View mutations
71 S 2 17 19 0.895 0.566 View mutations
72 M 0 19 19 0.994 0.581 View mutations
73 T 0 19 19 1.000 0.716 View mutations
74 D 0 19 19 1.000 0.644 View mutations
75 K 0 19 19 0.999 0.552 View mutations