P61244 (MAX)

Overview
Predicted structure (AF):
AF-P61244-F1-model_v4
Uniprot entry:
P61244
Gene:
MAX
Protein length:
160 residues
Mutations found:
3039
Benign based on D2Deep prediction:
1752 out of 3039 mutations
Pathogenic based on D2Deep prediction:
1287 out of 3039 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3039 mutations across 160 unique positions. There are 1752 benign and 1287 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 R 1 18 19 0.933 0.598 View mutations
77 K 1 18 19 0.948 0.674 View mutations
78 N 0 19 19 1.000 0.678 View mutations
79 H 4 15 19 0.783 0.464 View mutations
80 T 2 17 19 0.909 0.543 View mutations
81 H 0 19 19 0.998 0.673 View mutations
82 Q 0 19 19 0.982 0.647 View mutations
83 Q 11 8 19 0.522 0.491 View mutations
84 D 12 7 19 0.419 0.465 View mutations
85 I 4 15 19 0.742 0.625 View mutations
86 D 17 2 19 0.114 0.374 View mutations
87 D 5 14 19 0.740 0.587 View mutations
88 L 3 16 19 0.784 0.673 View mutations
89 K 9 10 19 0.447 0.504 View mutations
90 R 19 0 19 0.006 0.474 View mutations
91 Q 12 7 19 0.434 0.456 View mutations
92 N 19 0 19 0.037 0.331 View mutations
93 A 16 3 19 0.180 0.374 View mutations
94 L 19 0 19 0.012 0.428 View mutations
95 L 4 15 19 0.694 0.578 View mutations
96 E 7 12 19 0.624 0.539 View mutations
97 Q 19 0 19 0.013 0.400 View mutations
98 Q 19 0 19 0.034 0.462 View mutations
99 V 18 1 19 0.116 0.438 View mutations
100 R 6 13 19 0.616 0.525 View mutations