P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 R 19 0 19 0.026 0.600 View mutations
177 A 17 2 19 0.100 0.617 View mutations
178 A 18 1 19 0.046 0.516 View mutations
179 L 19 0 19 0.004 0.564 View mutations
180 Q 19 0 19 0.002 0.820 View mutations
181 A 19 0 19 0.001 0.833 View mutations
182 R 19 0 19 0.000 0.827 View mutations
183 R 19 0 19 0.001 0.847 View mutations
184 G 19 0 19 0.002 0.881 View mutations
185 K 19 0 19 0.000 0.850 View mutations
186 K 19 0 19 0.001 0.871 View mutations
187 K 18 1 19 0.042 0.838 View mutations
188 S 19 0 19 0.001 0.896 View mutations
189 G 19 0 19 0.018 0.893 View mutations
190 C 18 1 19 0.111 0.600 View mutations
191 L 19 0 19 0.001 0.826 View mutations
192 V 19 0 19 0.008 0.725 View mutations
193 L 19 0 19 0.049 0.571 View mutations