P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.744 View mutations
2 A 19 0 19 0.019 0.936 View mutations
3 A 15 4 19 0.269 0.789 View mutations
4 I 19 0 19 0.099 0.877 View mutations
5 R 19 0 19 0.016 0.891 View mutations
6 K 19 0 19 0.003 0.778 View mutations
7 K 19 0 19 0.004 0.514 View mutations
8 L 19 0 19 0.010 0.510 View mutations
9 V 2 17 19 0.882 0.477 View mutations
10 I 11 8 19 0.387 0.441 View mutations
11 V 16 3 19 0.246 0.444 View mutations
12 G 3 16 19 0.857 0.612 View mutations
13 D 2 17 19 0.907 0.555 View mutations
14 G 0 19 19 0.995 0.512 View mutations
15 A 14 5 19 0.314 0.503 View mutations
16 C 19 0 19 0.001 0.468 View mutations
17 G 0 19 19 1.000 0.642 View mutations
18 K 0 19 19 1.000 0.536 View mutations
19 T 5 14 19 0.722 0.396 View mutations
20 C 13 6 19 0.381 0.573 View mutations
21 L 0 19 19 0.986 0.312 View mutations
22 L 10 9 19 0.518 0.488 View mutations
23 I 5 14 19 0.672 0.267 View mutations
24 V 2 17 19 0.844 0.242 View mutations
25 F 8 11 19 0.585 0.425 View mutations