P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 I 19 0 19 0.029 0.455 View mutations
152 G 11 8 19 0.429 0.474 View mutations
153 A 16 3 19 0.170 0.501 View mutations
154 F 19 0 19 0.001 0.759 View mutations
155 G 19 0 19 0.027 0.771 View mutations
156 Y 19 0 19 0.005 0.380 View mutations
157 M 19 0 19 0.001 0.482 View mutations
158 E 0 19 19 0.994 0.755 View mutations
159 C 18 1 19 0.072 0.484 View mutations
160 S 19 0 19 0.022 0.315 View mutations
161 A 2 17 19 0.888 0.544 View mutations
162 K 6 13 19 0.663 0.417 View mutations
163 T 17 2 19 0.215 0.587 View mutations
164 K 17 2 19 0.143 0.569 View mutations
165 D 18 1 19 0.063 0.572 View mutations
166 G 12 7 19 0.402 0.408 View mutations
167 V 19 0 19 0.000 0.469 View mutations
168 R 19 0 19 0.013 0.643 View mutations
169 E 19 0 19 0.004 0.556 View mutations
170 V 19 0 19 0.000 0.365 View mutations
171 F 0 19 19 0.987 0.519 View mutations
172 E 19 0 19 0.000 0.533 View mutations
173 M 19 0 19 0.016 0.806 View mutations
174 A 19 0 19 0.001 0.497 View mutations
175 T 18 1 19 0.059 0.479 View mutations