P61586 (RHOA)

Overview
Predicted structure (AF):
AF-P61586-F1-model_v4
Uniprot entry:
P61586
Gene:
RHOA
Protein length:
193 residues
Mutations found:
3666
Benign based on D2Deep prediction:
2470 out of 3666 mutations
Pathogenic based on D2Deep prediction:
1196 out of 3666 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3666 mutations across 193 unique positions. There are 2470 benign and 1196 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 H 19 0 19 0.001 0.888 View mutations
127 T 16 3 19 0.194 0.630 View mutations
128 R 17 2 19 0.188 0.689 View mutations
129 R 19 0 19 0.003 0.871 View mutations
130 E 16 3 19 0.187 0.754 View mutations
131 L 8 11 19 0.560 0.430 View mutations
132 A 19 0 19 0.018 0.821 View mutations
133 K 19 0 19 0.008 0.840 View mutations
134 M 19 0 19 0.011 0.837 View mutations
135 K 19 0 19 0.000 0.693 View mutations
136 Q 19 0 19 0.007 0.625 View mutations
137 E 19 0 19 0.008 0.671 View mutations
138 P 18 1 19 0.082 0.378 View mutations
139 V 18 1 19 0.054 0.410 View mutations
140 K 18 1 19 0.083 0.554 View mutations
141 P 19 0 19 0.002 0.740 View mutations
142 E 19 0 19 0.000 0.645 View mutations
143 E 19 0 19 0.000 0.650 View mutations
144 G 8 11 19 0.561 0.434 View mutations
145 R 19 0 19 0.001 0.788 View mutations
146 D 19 0 19 0.000 0.671 View mutations
147 M 14 5 19 0.239 0.523 View mutations
148 A 19 0 19 0.000 0.426 View mutations
149 N 19 0 19 0.000 0.743 View mutations
150 R 19 0 19 0.002 0.725 View mutations