P61769 (B2M)

Overview
Predicted structure (AF):
AF-P61769-F1-model_v4
Uniprot entry:
P61769
Gene:
B2M
Protein length:
119 residues
Mutations found:
2260
Benign based on D2Deep prediction:
1295 out of 2260 mutations
Pathogenic based on D2Deep prediction:
965 out of 2260 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 2260 mutations across 119 unique positions. There are 1295 benign and 965 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 F 0 19 19 0.982 0.917 View mutations
77 S 8 11 19 0.645 0.535 View mutations
78 K 1 18 19 0.946 0.623 View mutations
79 D 0 19 19 0.998 0.759 View mutations
80 W 0 19 19 1.000 0.841 View mutations
81 S 1 18 19 0.945 0.730 View mutations
82 F 0 19 19 1.000 0.765 View mutations
83 Y 1 18 19 0.954 0.595 View mutations
84 L 4 15 19 0.760 0.583 View mutations
85 L 11 8 19 0.462 0.450 View mutations
86 Y 18 1 19 0.129 0.422 View mutations
87 Y 10 9 19 0.494 0.497 View mutations
88 T 18 1 19 0.079 0.500 View mutations
89 E 19 0 19 0.013 0.353 View mutations
90 F 18 1 19 0.045 0.323 View mutations
91 T 16 3 19 0.184 0.477 View mutations
92 P 19 0 19 0.007 0.369 View mutations
93 T 18 1 19 0.085 0.577 View mutations
94 E 19 0 19 0.023 0.495 View mutations
95 K 17 2 19 0.142 0.624 View mutations
96 D 13 6 19 0.370 0.429 View mutations
97 E 16 3 19 0.212 0.513 View mutations
98 Y 2 17 19 0.818 0.560 View mutations
99 A 14 5 19 0.276 0.437 View mutations
100 C 0 19 19 1.000 0.858 View mutations