P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 V 4 15 19 0.755 0.519 View mutations
77 G 4 15 19 0.780 0.524 View mutations
78 E 1 18 19 0.946 0.581 View mutations
79 T 4 15 19 0.779 0.599 View mutations
80 Y 8 11 19 0.608 0.546 View mutations
81 G 2 17 19 0.876 0.710 View mutations
82 K 5 14 19 0.748 0.609 View mutations
83 D 0 19 19 0.997 0.760 View mutations
84 I 2 17 19 0.895 0.722 View mutations
85 T 4 15 19 0.778 0.665 View mutations
86 S 5 14 19 0.663 0.636 View mutations
87 R 1 18 19 0.958 0.745 View mutations
88 G 0 19 19 0.998 0.758 View mutations
89 K 1 18 19 0.954 0.629 View mutations
90 D 6 13 19 0.683 0.523 View mutations
91 K 4 15 19 0.822 0.463 View mutations
92 P 6 13 19 0.655 0.439 View mutations
93 I 9 10 19 0.538 0.431 View mutations
94 A 5 14 19 0.732 0.428 View mutations
95 D 0 19 19 0.994 0.361 View mutations
96 V 2 17 19 0.904 0.400 View mutations
97 F 0 19 19 0.995 0.407 View mutations
98 L 0 19 19 0.968 0.471 View mutations
99 I 1 18 19 0.950 0.481 View mutations
100 C 0 19 19 0.997 0.486 View mutations