P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 C 6 13 19 0.696 0.541 View mutations
177 S 1 18 19 0.953 0.706 View mutations
178 A 7 12 19 0.619 0.523 View mutations
179 L 13 6 19 0.299 0.408 View mutations
180 T 10 9 19 0.525 0.436 View mutations
181 Q 18 1 19 0.034 0.433 View mutations
182 R 19 0 19 0.010 0.591 View mutations
183 G 13 6 19 0.330 0.397 View mutations
184 L 12 7 19 0.400 0.438 View mutations
185 K 19 0 19 0.006 0.510 View mutations
186 T 19 0 19 0.004 0.530 View mutations
187 V 7 12 19 0.547 0.514 View mutations
188 F 13 6 19 0.337 0.475 View mutations
189 D 13 6 19 0.335 0.410 View mutations
190 E 19 0 19 0.013 0.660 View mutations
191 A 9 10 19 0.564 0.502 View mutations
192 I 14 5 19 0.289 0.404 View mutations
193 R 18 1 19 0.033 0.547 View mutations
194 A 17 2 19 0.099 0.538 View mutations
195 V 19 0 19 0.004 0.477 View mutations
196 L 19 0 19 0.000 0.472 View mutations
197 C 19 0 19 0.001 0.864 View mutations
198 P 19 0 19 0.006 0.723 View mutations
199 P 19 0 19 0.006 0.827 View mutations
200 P 18 1 19 0.062 0.736 View mutations