P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 N 13 6 19 0.270 0.499 View mutations
127 T 3 16 19 0.837 0.422 View mutations
128 P 0 19 19 1.000 0.504 View mutations
129 I 6 13 19 0.599 0.412 View mutations
130 I 2 17 19 0.897 0.573 View mutations
131 L 1 18 19 0.956 0.695 View mutations
132 V 1 18 19 0.928 0.662 View mutations
133 G 2 17 19 0.893 0.630 View mutations
134 T 4 15 19 0.730 0.618 View mutations
135 K 19 0 19 0.064 0.483 View mutations
136 L 18 1 19 0.128 0.531 View mutations
137 D 0 19 19 1.000 0.747 View mutations
138 L 3 16 19 0.831 0.621 View mutations
139 R 9 10 19 0.546 0.506 View mutations
140 D 15 4 19 0.239 0.550 View mutations
141 D 18 1 19 0.066 0.650 View mutations
142 K 19 0 19 0.002 0.845 View mutations
143 D 19 0 19 0.001 0.850 View mutations
144 T 18 1 19 0.052 0.697 View mutations
145 I 19 0 19 0.002 0.739 View mutations
146 E 19 0 19 0.003 0.958 View mutations
147 K 16 3 19 0.238 0.827 View mutations
148 L 19 0 19 0.000 0.654 View mutations
149 K 19 0 19 0.022 0.843 View mutations
150 E 19 0 19 0.001 0.955 View mutations