P63000-2 (RAC1)

Overview
Predicted structure (AF):
AF-P63000-2-F1-model_v4
Uniprot entry:
P63000-2
Gene:
RAC1
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
2097 out of 4008 mutations
Pathogenic based on D2Deep prediction:
1911 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4008 mutations across 211 unique positions. There are 2097 benign and 1911 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 18 1 19 0.055 0.783 View mutations
152 K 12 7 19 0.409 0.530 View mutations
153 L 18 1 19 0.065 0.662 View mutations
154 T 19 0 19 0.075 0.693 View mutations
155 P 4 15 19 0.780 0.511 View mutations
156 I 13 6 19 0.337 0.409 View mutations
157 T 19 0 19 0.002 0.457 View mutations
158 Y 19 0 19 0.033 0.677 View mutations
159 P 19 0 19 0.003 0.652 View mutations
160 Q 19 0 19 0.009 0.605 View mutations
161 G 1 18 19 0.921 0.485 View mutations
162 L 17 2 19 0.184 0.634 View mutations
163 A 19 0 19 0.026 0.623 View mutations
164 M 13 6 19 0.357 0.478 View mutations
165 A 19 0 19 0.052 0.408 View mutations
166 K 18 1 19 0.071 0.610 View mutations
167 E 19 0 19 0.000 0.671 View mutations
168 I 5 14 19 0.734 0.441 View mutations
169 G 19 0 19 0.002 0.534 View mutations
170 A 19 0 19 0.052 0.556 View mutations
171 V 13 6 19 0.329 0.517 View mutations
172 K 18 1 19 0.070 0.635 View mutations
173 Y 18 1 19 0.247 0.480 View mutations
174 L 18 1 19 0.126 0.492 View mutations
175 E 7 12 19 0.651 0.562 View mutations