P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.387 View mutations
2 A 18 1 19 0.088 0.691 View mutations
3 R 3 16 19 0.818 0.268 View mutations
4 T 16 3 19 0.224 0.637 View mutations
5 K 19 0 19 0.011 0.688 View mutations
6 Q 19 0 19 0.006 0.713 View mutations
7 T 19 0 19 0.000 0.801 View mutations
8 A 19 0 19 0.001 0.795 View mutations
9 R 19 0 19 0.018 0.809 View mutations
10 K 19 0 19 0.012 0.728 View mutations
11 S 19 0 19 0.000 0.802 View mutations
12 T 17 2 19 0.142 0.737 View mutations
13 G 19 0 19 0.004 0.830 View mutations
14 G 13 6 19 0.333 0.577 View mutations
15 K 19 0 19 0.005 0.833 View mutations
16 A 19 0 19 0.000 0.819 View mutations
17 P 9 10 19 0.496 0.460 View mutations
18 R 13 6 19 0.333 0.634 View mutations
19 K 11 8 19 0.396 0.553 View mutations
20 Q 19 0 19 0.000 0.938 View mutations
21 L 1 18 19 0.914 0.177 View mutations
22 A 19 0 19 0.002 0.897 View mutations
23 T 18 1 19 0.148 0.860 View mutations
24 K 18 1 19 0.082 0.845 View mutations
25 A 14 5 19 0.337 0.675 View mutations