P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 0 19 19 1.000 0.705 View mutations
52 I 0 19 19 0.980 0.956 View mutations
53 R 0 19 19 1.000 0.740 View mutations
54 R 18 1 19 0.083 0.489 View mutations
55 Y 19 0 19 0.000 0.296 View mutations
56 Q 10 9 19 0.460 0.484 View mutations
57 K 5 14 19 0.731 0.523 View mutations
58 S 19 0 19 0.007 0.439 View mutations
59 T 19 0 19 0.003 0.312 View mutations
60 E 19 0 19 0.031 0.486 View mutations
61 L 1 18 19 0.858 0.655 View mutations
62 L 0 19 19 0.978 0.719 View mutations
63 I 19 0 19 0.044 0.302 View mutations
64 R 19 0 19 0.039 0.495 View mutations
65 K 16 3 19 0.246 0.460 View mutations
66 L 10 9 19 0.478 0.488 View mutations
67 P 1 18 19 0.945 0.815 View mutations
68 F 3 16 19 0.811 0.758 View mutations
69 Q 19 0 19 0.000 0.281 View mutations
70 R 19 0 19 0.000 0.224 View mutations
71 L 0 19 19 0.992 0.775 View mutations
72 V 6 13 19 0.569 0.598 View mutations
73 R 1 18 19 0.946 0.587 View mutations
74 E 16 3 19 0.223 0.379 View mutations
75 I 19 0 19 0.098 0.407 View mutations