P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 Q 19 0 19 0.110 0.386 View mutations
127 L 1 18 19 0.962 0.947 View mutations
128 A 0 19 19 1.000 0.893 View mutations
129 R 18 1 19 0.064 0.345 View mutations
130 R 2 17 19 0.929 0.654 View mutations
131 I 4 15 19 0.826 0.676 View mutations
132 R 7 12 19 0.570 0.533 View mutations
133 G 19 0 19 0.117 0.287 View mutations
134 E 19 0 19 0.012 0.459 View mutations
135 R 19 0 19 0.000 0.409 View mutations
136 A 18 1 19 0.053 0.494 View mutations