P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 A 19 0 19 0.000 0.919 View mutations
27 R 19 0 19 0.000 0.959 View mutations
28 K 15 4 19 0.238 0.731 View mutations
29 S 17 2 19 0.143 0.895 View mutations
30 A 19 0 19 0.035 0.883 View mutations
31 P 19 0 19 0.000 0.777 View mutations
32 A 19 0 19 0.003 0.934 View mutations
33 T 18 1 19 0.089 0.734 View mutations
34 G 19 0 19 0.000 0.737 View mutations
35 G 12 7 19 0.349 0.544 View mutations
36 V 19 0 19 0.001 0.749 View mutations
37 K 19 0 19 0.000 0.827 View mutations
38 K 4 15 19 0.805 0.335 View mutations
39 P 2 17 19 0.870 0.354 View mutations
40 H 18 1 19 0.052 0.470 View mutations
41 R 13 6 19 0.317 0.414 View mutations
42 Y 19 0 19 0.003 0.465 View mutations
43 R 19 0 19 0.000 0.418 View mutations
44 P 11 8 19 0.463 0.456 View mutations
45 G 2 17 19 0.903 0.694 View mutations
46 T 3 16 19 0.880 0.576 View mutations
47 V 8 11 19 0.543 0.506 View mutations
48 A 11 8 19 0.474 0.462 View mutations
49 L 0 19 19 0.952 0.824 View mutations
50 R 0 19 19 0.996 0.563 View mutations