P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 L 19 0 19 0.014 0.054 View mutations
102 V 7 12 19 0.606 0.571 View mutations
103 G 3 16 19 0.823 0.561 View mutations
104 L 0 19 19 1.000 0.888 View mutations
105 F 0 19 19 1.000 0.828 View mutations
106 E 10 9 19 0.465 0.485 View mutations
107 D 19 0 19 0.003 0.274 View mutations
108 T 6 13 19 0.698 0.590 View mutations
109 N 19 0 19 0.000 0.243 View mutations
110 L 19 0 19 0.014 0.199 View mutations
111 C 18 1 19 0.060 0.221 View mutations
112 A 15 4 19 0.311 0.281 View mutations
113 I 19 0 19 0.015 0.221 View mutations
114 H 2 17 19 0.851 0.835 View mutations
115 A 3 16 19 0.875 0.753 View mutations
116 K 18 1 19 0.105 0.289 View mutations
117 R 4 15 19 0.805 0.756 View mutations
118 V 19 0 19 0.004 0.168 View mutations
119 T 10 9 19 0.526 0.482 View mutations
120 I 18 1 19 0.056 0.218 View mutations
121 M 14 5 19 0.299 0.491 View mutations
122 P 19 0 19 0.019 0.316 View mutations
123 K 8 11 19 0.495 0.514 View mutations
124 D 4 15 19 0.762 0.751 View mutations
125 I 11 8 19 0.480 0.468 View mutations