P68431 (H3C2)

Overview
Predicted structure (AF):
AF-P68431-F1-model_v4
Uniprot entry:
P68431
Gene:
H3C2
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1626 out of 2583 mutations
Pathogenic based on D2Deep prediction:
957 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1626 benign and 957 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 6 13 19 0.577 0.525 View mutations
77 Q 19 0 19 0.017 0.371 View mutations
78 D 0 19 19 0.979 0.455 View mutations
79 F 5 14 19 0.727 0.460 View mutations
80 K 15 4 19 0.270 0.546 View mutations
81 T 9 10 19 0.476 0.430 View mutations
82 D 1 18 19 0.880 0.459 View mutations
83 L 5 14 19 0.723 0.523 View mutations
84 R 19 0 19 0.003 0.385 View mutations
85 F 11 8 19 0.448 0.415 View mutations
86 Q 19 0 19 0.006 0.436 View mutations
87 S 4 15 19 0.799 0.358 View mutations
88 S 14 5 19 0.285 0.575 View mutations
89 A 19 0 19 0.013 0.377 View mutations
90 V 19 0 19 0.000 0.462 View mutations
91 M 17 2 19 0.101 0.810 View mutations
92 A 19 0 19 0.000 0.296 View mutations
93 L 5 14 19 0.687 0.709 View mutations
94 Q 19 0 19 0.053 0.111 View mutations
95 E 1 18 19 0.946 0.800 View mutations
96 A 0 19 19 1.000 0.665 View mutations
97 C 11 8 19 0.411 0.496 View mutations
98 E 0 19 19 0.890 0.899 View mutations
99 A 0 19 19 1.000 0.673 View mutations
100 Y 0 19 19 0.971 0.581 View mutations