P84243 (P84243)

Overview
Predicted structure (AF):
AF-P84243-F1-model_v4
Uniprot entry:
P84243
Gene:
P84243
Protein length:
136 residues
Mutations found:
2583
Benign based on D2Deep prediction:
1722 out of 2583 mutations
Pathogenic based on D2Deep prediction:
861 out of 2583 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2583 mutations across 136 unique positions. There are 1722 benign and 861 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 15 4 19 0.246 0.441 View mutations
77 Q 19 0 19 0.019 0.492 View mutations
78 D 0 19 19 0.975 0.480 View mutations
79 F 8 11 19 0.587 0.506 View mutations
80 K 17 2 19 0.121 0.569 View mutations
81 T 8 11 19 0.547 0.501 View mutations
82 D 5 14 19 0.767 0.445 View mutations
83 L 15 4 19 0.276 0.459 View mutations
84 R 19 0 19 0.000 0.482 View mutations
85 F 14 5 19 0.316 0.487 View mutations
86 Q 19 0 19 0.000 0.404 View mutations
87 S 6 13 19 0.724 0.403 View mutations
88 A 13 6 19 0.318 0.536 View mutations
89 A 19 0 19 0.027 0.326 View mutations
90 I 19 0 19 0.000 0.396 View mutations
91 G 16 3 19 0.147 0.736 View mutations
92 A 19 0 19 0.000 0.283 View mutations
93 L 6 13 19 0.715 0.676 View mutations
94 Q 19 0 19 0.011 0.072 View mutations
95 E 0 19 19 0.967 0.869 View mutations
96 A 0 19 19 0.977 0.704 View mutations
97 S 17 2 19 0.120 0.444 View mutations
98 E 8 11 19 0.530 0.572 View mutations
99 A 0 19 19 0.996 0.710 View mutations
100 Y 1 18 19 0.913 0.583 View mutations