Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.083 0.385 View mutations
2 S 4 15 19 0.796 0.551 View mutations
3 Y 0 19 19 0.993 0.551 View mutations
4 G 13 6 19 0.401 0.460 View mutations
5 R 7 12 19 0.631 0.509 View mutations
6 P 18 1 19 0.114 0.403 View mutations
7 P 19 0 19 0.074 0.283 View mutations
8 P 16 3 19 0.206 0.329 View mutations
9 D 19 0 19 0.028 0.347 View mutations
10 V 11 8 19 0.398 0.468 View mutations
11 E 19 0 19 0.006 0.284 View mutations
12 G 9 10 19 0.486 0.515 View mutations
13 M 5 14 19 0.739 0.640 View mutations
14 T 15 4 19 0.167 0.298 View mutations
15 S 15 4 19 0.315 0.299 View mutations
16 L 6 13 19 0.685 0.621 View mutations
17 K 1 18 19 0.928 0.789 View mutations
18 V 1 18 19 0.812 0.835 View mutations
19 D 0 19 19 1.000 0.894 View mutations
20 N 0 19 19 0.998 0.914 View mutations
21 L 0 19 19 0.996 1.000 View mutations
22 T 0 19 19 0.995 0.828 View mutations
23 Y 0 19 19 0.993 0.791 View mutations
24 R 0 19 19 0.999 0.691 View mutations
25 T 0 19 19 1.000 0.748 View mutations