Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 T 0 19 19 0.981 0.859 View mutations
52 K 0 19 19 0.999 0.746 View mutations
53 E 0 19 19 1.000 0.786 View mutations
54 S 0 19 19 1.000 0.838 View mutations
55 R 1 18 19 0.948 0.759 View mutations
56 G 0 19 19 0.999 0.911 View mutations
57 F 0 19 19 1.000 0.898 View mutations
58 A 0 19 19 1.000 0.930 View mutations
59 F 0 19 19 1.000 0.875 View mutations
60 V 0 19 19 0.983 0.907 View mutations
61 R 0 19 19 1.000 0.789 View mutations
62 F 0 19 19 1.000 0.715 View mutations
63 H 1 18 19 0.919 0.568 View mutations
64 D 0 19 19 0.997 0.669 View mutations
65 K 2 17 19 0.905 0.640 View mutations
66 R 2 17 19 0.869 0.593 View mutations
67 D 0 19 19 0.999 0.715 View mutations
68 A 0 19 19 0.993 0.811 View mutations
69 E 1 18 19 0.947 0.694 View mutations
70 D 0 19 19 0.959 0.669 View mutations
71 A 0 19 19 1.000 0.843 View mutations
72 M 1 18 19 0.964 0.676 View mutations
73 D 0 19 19 0.998 0.645 View mutations
74 A 0 19 19 0.984 0.719 View mutations
75 M 0 19 19 1.000 0.689 View mutations