Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 3 16 19 0.821 0.594 View mutations
27 P 0 19 19 0.970 0.718 View mutations
28 D 5 14 19 0.675 0.570 View mutations
29 T 1 18 19 0.927 0.665 View mutations
30 L 0 19 19 0.996 0.755 View mutations
31 R 1 18 19 0.900 0.683 View mutations
32 R 7 12 19 0.527 0.543 View mutations
33 V 0 19 19 1.000 0.767 View mutations
34 F 0 19 19 1.000 0.848 View mutations
35 E 1 18 19 0.957 0.716 View mutations
36 K 1 18 19 0.925 0.647 View mutations
37 Y 1 18 19 0.963 0.785 View mutations
38 G 0 19 19 1.000 0.804 View mutations
39 R 3 16 19 0.897 0.586 View mutations
40 V 0 19 19 0.998 0.848 View mutations
41 G 0 19 19 1.000 0.825 View mutations
42 D 1 18 19 0.950 0.939 View mutations
43 V 5 14 19 0.782 0.690 View mutations
44 Y 0 19 19 0.989 0.842 View mutations
45 I 0 19 19 0.994 0.846 View mutations
46 P 0 19 19 1.000 0.832 View mutations
47 R 0 19 19 0.983 0.719 View mutations
48 D 0 19 19 1.000 0.741 View mutations
49 R 0 19 19 0.978 0.718 View mutations
50 Y 0 19 19 0.986 0.666 View mutations