Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 K 19 0 19 0.014 0.898 View mutations
202 S 15 4 19 0.260 0.708 View mutations
203 R 18 1 19 0.063 0.837 View mutations
204 S 19 0 19 0.000 0.841 View mutations
205 R 19 0 19 0.062 0.875 View mutations
206 S 19 0 19 0.007 0.824 View mutations
207 K 17 2 19 0.189 0.751 View mutations
208 S 16 3 19 0.246 0.724 View mutations
209 P 18 1 19 0.065 0.790 View mutations
210 P 19 0 19 0.016 0.780 View mutations
211 K 19 0 19 0.053 0.685 View mutations
212 S 2 17 19 0.805 0.222 View mutations
213 P 14 5 19 0.304 0.586 View mutations
214 E 9 10 19 0.478 0.455 View mutations
215 E 19 0 19 0.111 0.736 View mutations
216 E 11 8 19 0.342 0.522 View mutations
217 G 19 0 19 0.124 0.758 View mutations
218 A 17 2 19 0.104 0.710 View mutations
219 V 19 0 19 0.006 0.783 View mutations
220 S 19 0 19 0.001 0.738 View mutations
221 S 19 0 19 0.000 0.686 View mutations