Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 S 19 0 19 0.016 0.928 View mutations
152 R 19 0 19 0.098 0.927 View mutations
153 T 19 0 19 0.103 0.940 View mutations
154 R 19 0 19 0.000 0.928 View mutations
155 S 19 0 19 0.103 0.972 View mutations
156 R 19 0 19 0.015 0.932 View mutations
157 S 19 0 19 0.003 0.982 View mutations
158 R 19 0 19 0.013 0.971 View mutations
159 S 19 0 19 0.007 0.958 View mutations
160 T 19 0 19 0.006 0.975 View mutations
161 S 19 0 19 0.007 0.978 View mutations
162 K 19 0 19 0.044 0.970 View mutations
163 S 19 0 19 0.005 0.995 View mutations
164 R 19 0 19 0.003 0.971 View mutations
165 S 19 0 19 0.001 0.965 View mutations
166 A 19 0 19 0.003 0.973 View mutations
167 R 19 0 19 0.001 0.959 View mutations
168 R 19 0 19 0.007 0.979 View mutations
169 S 19 0 19 0.001 0.933 View mutations
170 K 19 0 19 0.001 0.944 View mutations
171 S 19 0 19 0.003 0.950 View mutations
172 K 19 0 19 0.000 0.959 View mutations
173 S 19 0 19 0.001 0.950 View mutations
174 S 19 0 19 0.000 0.931 View mutations
175 S 19 0 19 0.006 0.942 View mutations