Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 V 19 0 19 0.000 0.934 View mutations
177 S 19 0 19 0.000 0.939 View mutations
178 R 19 0 19 0.000 0.914 View mutations
179 S 19 0 19 0.001 0.930 View mutations
180 R 19 0 19 0.001 0.929 View mutations
181 S 19 0 19 0.000 0.927 View mutations
182 R 19 0 19 0.000 0.927 View mutations
183 S 19 0 19 0.001 0.909 View mutations
184 R 19 0 19 0.000 0.959 View mutations
185 S 19 0 19 0.004 0.930 View mutations
186 R 19 0 19 0.002 0.964 View mutations
187 S 19 0 19 0.014 0.932 View mutations
188 R 19 0 19 0.009 0.957 View mutations
189 S 19 0 19 0.025 0.961 View mutations
190 R 19 0 19 0.007 0.963 View mutations
191 S 19 0 19 0.059 0.941 View mutations
192 P 19 0 19 0.004 0.995 View mutations
193 P 19 0 19 0.006 0.990 View mutations
194 P 19 0 19 0.007 0.970 View mutations
195 V 19 0 19 0.001 0.961 View mutations
196 S 19 0 19 0.004 0.960 View mutations
197 K 19 0 19 0.002 0.941 View mutations
198 R 15 4 19 0.161 0.744 View mutations
199 E 19 0 19 0.000 0.919 View mutations
200 S 18 1 19 0.111 0.865 View mutations