Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 S 10 9 19 0.478 0.433 View mutations
227 W 6 13 19 0.695 0.533 View mutations
228 Q 7 12 19 0.648 0.522 View mutations
229 G 0 19 19 1.000 0.727 View mutations
230 E 0 19 19 1.000 0.714 View mutations
231 N 8 11 19 0.576 0.506 View mutations
232 V 1 18 19 0.949 0.716 View mutations
233 A 0 19 19 1.000 0.881 View mutations
234 V 0 19 19 1.000 0.813 View mutations
235 K 0 19 19 0.982 0.828 View mutations
236 I 7 12 19 0.604 0.576 View mutations
237 F 0 19 19 1.000 0.881 View mutations
238 S 0 19 19 1.000 0.792 View mutations
239 S 0 19 19 1.000 0.831 View mutations
240 R 1 18 19 0.964 0.758 View mutations
241 D 0 19 19 0.987 0.833 View mutations
242 E 1 18 19 0.947 0.790 View mutations
243 K 3 16 19 0.824 0.540 View mutations
244 S 12 7 19 0.352 0.410 View mutations
245 W 0 19 19 0.987 0.811 View mutations
246 F 3 16 19 0.852 0.614 View mutations
247 R 3 16 19 0.817 0.726 View mutations
248 E 0 19 19 1.000 0.907 View mutations
249 T 0 19 19 1.000 0.831 View mutations
250 E 0 19 19 1.000 0.809 View mutations