Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 S 0 19 19 0.972 0.767 View mutations
277 T 11 8 19 0.467 0.431 View mutations
278 Q 5 14 19 0.710 0.653 View mutations
279 L 0 19 19 0.995 0.889 View mutations
280 W 0 19 19 1.000 0.772 View mutations
281 L 0 19 19 1.000 0.836 View mutations
282 I 1 18 19 0.946 0.664 View mutations
283 T 0 19 19 1.000 0.760 View mutations
284 H 0 19 19 0.992 0.670 View mutations
285 Y 1 18 19 0.948 0.633 View mutations
286 H 0 19 19 0.973 0.679 View mutations
287 E 10 9 19 0.495 0.497 View mutations
288 M 5 14 19 0.700 0.550 View mutations
289 G 3 16 19 0.814 0.786 View mutations
290 S 0 19 19 1.000 0.912 View mutations
291 L 0 19 19 1.000 0.810 View mutations
292 Y 0 19 19 1.000 0.761 View mutations
293 D 4 15 19 0.773 0.627 View mutations
294 Y 2 17 19 0.918 0.535 View mutations
295 L 5 14 19 0.673 0.616 View mutations
296 Q 19 0 19 0.003 0.469 View mutations
297 L 15 4 19 0.233 0.472 View mutations
298 T 10 9 19 0.406 0.442 View mutations
299 T 16 3 19 0.173 0.423 View mutations
300 L 3 16 19 0.848 0.538 View mutations