Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 Q 0 19 19 0.982 0.675 View mutations
202 R 8 11 19 0.580 0.533 View mutations
203 T 19 0 19 0.002 0.328 View mutations
204 V 18 1 19 0.052 0.380 View mutations
205 A 2 17 19 0.901 0.634 View mutations
206 R 1 18 19 0.950 0.574 View mutations
207 Q 0 19 19 1.000 0.562 View mutations
208 I 1 18 19 0.926 0.530 View mutations
209 T 8 11 19 0.566 0.435 View mutations
210 L 12 7 19 0.427 0.482 View mutations
211 L 16 3 19 0.191 0.418 View mutations
212 E 0 19 19 1.000 0.598 View mutations
213 C 0 19 19 0.999 0.530 View mutations
214 V 1 18 19 0.965 0.644 View mutations
215 G 0 19 19 1.000 0.723 View mutations
216 K 0 19 19 1.000 0.714 View mutations
217 G 0 19 19 1.000 0.807 View mutations
218 R 3 16 19 0.808 0.642 View mutations
219 Y 7 12 19 0.569 0.561 View mutations
220 G 11 8 19 0.436 0.448 View mutations
221 E 19 0 19 0.033 0.228 View mutations
222 V 0 19 19 1.000 0.796 View mutations
223 W 17 2 19 0.111 0.346 View mutations
224 R 8 11 19 0.606 0.505 View mutations
225 G 0 19 19 0.993 0.694 View mutations