Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 G 14 5 19 0.308 0.456 View mutations
177 D 13 6 19 0.350 0.454 View mutations
178 S 19 0 19 0.029 0.468 View mutations
179 T 17 2 19 0.118 0.493 View mutations
180 L 9 10 19 0.492 0.435 View mutations
181 A 19 0 19 0.007 0.512 View mutations
182 D 17 2 19 0.136 0.460 View mutations
183 L 12 7 19 0.387 0.461 View mutations
184 L 13 6 19 0.354 0.459 View mutations
185 D 19 0 19 0.015 0.491 View mutations
186 H 19 0 19 0.001 0.526 View mutations
187 S 10 9 19 0.468 0.428 View mutations
188 C 12 7 19 0.395 0.430 View mutations
189 T 0 19 19 0.974 0.557 View mutations
190 S 10 9 19 0.485 0.495 View mutations
191 G 0 19 19 1.000 0.652 View mutations
192 S 0 19 19 0.999 0.634 View mutations
193 G 0 19 19 0.995 0.674 View mutations
194 S 1 18 19 0.949 0.661 View mutations
195 G 0 19 19 0.953 0.734 View mutations
196 L 18 1 19 0.113 0.305 View mutations
197 P 2 17 19 0.868 0.698 View mutations
198 F 2 17 19 0.871 0.631 View mutations
199 L 6 13 19 0.654 0.585 View mutations
200 V 0 19 19 0.992 0.728 View mutations