Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 D 2 17 19 0.835 0.425 View mutations
302 T 19 0 19 0.000 0.512 View mutations
303 V 12 7 19 0.406 0.506 View mutations
304 S 9 10 19 0.521 0.441 View mutations
305 C 19 0 19 0.000 0.453 View mutations
306 L 18 1 19 0.060 0.498 View mutations
307 R 16 3 19 0.150 0.535 View mutations
308 I 18 1 19 0.079 0.473 View mutations
309 V 19 0 19 0.001 0.455 View mutations
310 L 15 4 19 0.254 0.521 View mutations
311 S 11 8 19 0.425 0.493 View mutations
312 I 19 0 19 0.004 0.489 View mutations
313 A 19 0 19 0.069 0.356 View mutations
314 S 6 13 19 0.699 0.438 View mutations
315 G 0 19 19 0.999 0.700 View mutations
316 L 15 4 19 0.204 0.405 View mutations
317 A 12 7 19 0.414 0.498 View mutations
318 H 17 2 19 0.122 0.348 View mutations
319 L 2 17 19 0.855 0.712 View mutations
320 H 6 13 19 0.730 0.579 View mutations
321 I 8 11 19 0.490 0.503 View mutations
322 E 5 14 19 0.686 0.612 View mutations
323 I 5 14 19 0.753 0.589 View mutations
324 F 0 19 19 0.976 0.597 View mutations
325 G 0 19 19 0.999 0.624 View mutations