Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 T 4 15 19 0.766 0.542 View mutations
327 Q 8 11 19 0.567 0.503 View mutations
328 G 0 19 19 0.999 0.726 View mutations
329 K 0 19 19 0.991 0.721 View mutations
330 P 3 16 19 0.879 0.659 View mutations
331 A 0 19 19 1.000 0.767 View mutations
332 I 0 19 19 1.000 0.816 View mutations
333 A 1 18 19 0.947 0.776 View mutations
334 H 0 19 19 1.000 0.823 View mutations
335 R 0 19 19 1.000 0.868 View mutations
336 D 0 19 19 1.000 0.765 View mutations
337 L 5 14 19 0.727 0.627 View mutations
338 K 0 19 19 1.000 0.826 View mutations
339 S 10 9 19 0.502 0.484 View mutations
340 K 1 18 19 0.947 0.715 View mutations
341 N 8 11 19 0.530 0.541 View mutations
342 I 7 12 19 0.656 0.537 View mutations
343 L 0 19 19 1.000 0.730 View mutations
344 V 0 19 19 0.977 0.582 View mutations
345 K 16 3 19 0.172 0.387 View mutations
346 K 15 4 19 0.190 0.441 View mutations
347 N 10 9 19 0.509 0.425 View mutations
348 G 6 13 19 0.744 0.504 View mutations
349 Q 9 10 19 0.537 0.432 View mutations
350 C 0 19 19 0.969 0.620 View mutations