Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 R 19 0 19 0.008 0.706 View mutations
152 R 18 1 19 0.052 0.705 View mutations
153 N 19 0 19 0.004 0.735 View mutations
154 Q 19 0 19 0.002 0.711 View mutations
155 E 18 1 19 0.076 0.662 View mutations
156 R 19 0 19 0.003 0.707 View mutations
157 L 19 0 19 0.001 0.727 View mutations
158 N 19 0 19 0.042 0.751 View mutations
159 P 19 0 19 0.003 0.722 View mutations
160 R 19 0 19 0.000 0.691 View mutations
161 D 19 0 19 0.014 0.644 View mutations
162 V 14 5 19 0.258 0.579 View mutations
163 E 19 0 19 0.016 0.678 View mutations
164 Y 16 3 19 0.206 0.625 View mutations
165 G 19 0 19 0.001 0.674 View mutations
166 T 19 0 19 0.008 0.699 View mutations
167 I 19 0 19 0.000 0.692 View mutations
168 E 17 2 19 0.069 0.621 View mutations
169 G 19 0 19 0.029 0.661 View mutations
170 L 19 0 19 0.079 0.603 View mutations
171 I 13 6 19 0.370 0.489 View mutations
172 T 19 0 19 0.003 0.567 View mutations
173 T 19 0 19 0.004 0.567 View mutations
174 N 19 0 19 0.000 0.584 View mutations
175 V 19 0 19 0.003 0.563 View mutations