O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 A 19 0 19 0.004 0.878 View mutations
277 G 19 0 19 0.002 0.772 View mutations
278 M 19 0 19 0.003 0.814 View mutations
279 L 6 13 19 0.692 0.399 View mutations
280 S 18 1 19 0.060 0.701 View mutations
281 F 1 18 19 0.844 0.344 View mutations
282 G 19 0 19 0.029 0.628 View mutations
283 G 19 0 19 0.037 0.602 View mutations
284 R 4 15 19 0.747 0.412 View mutations
285 L 15 4 19 0.217 0.396 View mutations
286 D 19 0 19 0.000 0.474 View mutations
287 V 19 0 19 0.001 0.519 View mutations
288 P 16 3 19 0.134 0.453 View mutations
289 K 15 4 19 0.186 0.521 View mutations
290 Q 9 10 19 0.557 0.442 View mutations
291 S 18 1 19 0.093 0.621 View mutations
292 S 11 8 19 0.436 0.488 View mutations
293 Q 19 0 19 0.000 0.674 View mutations
294 R 15 4 19 0.202 0.625 View mutations
295 G 19 0 19 0.000 0.603 View mutations
296 L 19 0 19 0.000 0.676 View mutations
297 T 11 8 19 0.432 0.488 View mutations
298 A 7 12 19 0.613 0.500 View mutations
299 R 10 9 19 0.479 0.439 View mutations
300 E 8 11 19 0.651 0.432 View mutations