O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 0 19 19 0.989 0.668 View mutations
77 Y 2 17 19 0.884 0.651 View mutations
78 V 0 19 19 1.000 0.689 View mutations
79 W 0 19 19 0.992 0.580 View mutations
80 T 3 16 19 0.860 0.410 View mutations
81 L 5 14 19 0.690 0.403 View mutations
82 K 2 17 19 0.857 0.338 View mutations
83 G 13 6 19 0.345 0.449 View mutations
84 R 19 0 19 0.019 0.560 View mutations
85 T 18 1 19 0.034 0.477 View mutations
86 W 12 7 19 0.427 0.490 View mutations
87 K 3 16 19 0.804 0.530 View mutations
88 P 9 10 19 0.532 0.511 View mutations
89 T 19 0 19 0.017 0.336 View mutations
90 L 19 0 19 0.001 0.169 View mutations
91 V 14 5 19 0.350 0.369 View mutations
92 I 19 0 19 0.002 0.232 View mutations
93 L 1 18 19 0.894 0.800 View mutations
94 R 16 3 19 0.242 0.251 View mutations
95 I 0 19 19 0.970 0.902 View mutations
96 N 0 19 19 0.926 0.866 View mutations
97 R 10 9 19 0.491 0.487 View mutations
98 A 11 8 19 0.482 0.451 View mutations
99 A 0 19 19 0.958 0.810 View mutations
100 R 7 12 19 0.670 0.548 View mutations