O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 P 0 19 19 1.000 0.643 View mutations
27 G 4 15 19 0.771 0.608 View mutations
28 E 1 18 19 0.943 0.563 View mutations
29 E 0 19 19 0.998 0.599 View mutations
30 G 0 19 19 0.986 0.540 View mutations
31 E 12 7 19 0.361 0.459 View mutations
32 L 12 7 19 0.387 0.453 View mutations
33 V 13 6 19 0.385 0.482 View mutations
34 S 16 3 19 0.120 0.621 View mutations
35 T 17 2 19 0.088 0.610 View mutations
36 D 14 5 19 0.267 0.560 View mutations
37 P 19 0 19 0.001 0.665 View mutations
38 R 13 6 19 0.285 0.550 View mutations
39 P 14 5 19 0.279 0.592 View mutations
40 A 19 0 19 0.007 0.818 View mutations
41 S 16 3 19 0.143 0.683 View mutations
42 Y 19 0 19 0.005 0.778 View mutations
43 S 19 0 19 0.001 0.759 View mutations
44 F 19 0 19 0.010 0.741 View mutations
45 C 13 6 19 0.292 0.564 View mutations
46 S 17 2 19 0.096 0.709 View mutations
47 G 18 1 19 0.058 0.685 View mutations
48 K 17 2 19 0.126 0.635 View mutations
49 G 18 1 19 0.041 0.749 View mutations
50 V 14 5 19 0.297 0.613 View mutations