O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 G 13 6 19 0.319 0.575 View mutations
52 I 18 1 19 0.152 0.680 View mutations
53 K 4 15 19 0.760 0.358 View mutations
54 G 17 2 19 0.123 0.670 View mutations
55 E 13 6 19 0.375 0.490 View mutations
56 T 12 7 19 0.411 0.487 View mutations
57 S 1 18 19 0.935 0.330 View mutations
58 T 8 11 19 0.525 0.433 View mutations
59 A 5 14 19 0.730 0.501 View mutations
60 T 0 19 19 0.996 0.568 View mutations
61 P 0 19 19 1.000 0.634 View mutations
62 R 0 19 19 1.000 0.586 View mutations
63 R 1 18 19 0.825 0.635 View mutations
64 S 6 13 19 0.702 0.567 View mutations
65 D 1 18 19 0.944 0.780 View mutations
66 L 0 19 19 0.942 0.777 View mutations
67 D 0 19 19 0.998 0.823 View mutations
68 L 0 19 19 0.989 0.812 View mutations
69 G 0 19 19 0.973 0.942 View mutations
70 Y 0 19 19 0.981 0.858 View mutations
71 E 0 19 19 1.000 0.912 View mutations
72 P 0 19 19 1.000 0.923 View mutations
73 E 0 19 19 1.000 0.854 View mutations
74 G 0 19 19 1.000 0.948 View mutations
75 S 0 19 19 0.999 0.818 View mutations