O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 0 19 19 1.000 0.848 View mutations
77 S 0 19 19 0.994 0.886 View mutations
78 P 0 19 19 1.000 0.920 View mutations
79 T 0 19 19 1.000 0.872 View mutations
80 P 0 19 19 1.000 0.860 View mutations
81 P 0 19 19 1.000 0.900 View mutations
82 Y 0 19 19 0.996 0.788 View mutations
83 L 2 17 19 0.925 0.804 View mutations
84 K 1 18 19 0.947 0.769 View mutations
85 W 0 19 19 1.000 0.864 View mutations
86 A 1 18 19 0.894 0.929 View mutations
87 E 2 17 19 0.908 0.853 View mutations
88 S 7 12 19 0.620 0.632 View mutations
89 L 1 18 19 0.926 0.866 View mutations
90 H 3 16 19 0.809 0.831 View mutations
91 S 5 14 19 0.727 0.714 View mutations
92 L 9 10 19 0.545 0.524 View mutations
93 L 0 19 19 0.998 0.933 View mutations
94 D 3 16 19 0.843 0.840 View mutations
95 D 0 19 19 1.000 0.882 View mutations
96 Q 3 16 19 0.856 0.644 View mutations
97 D 5 14 19 0.651 0.600 View mutations
98 G 8 11 19 0.575 0.553 View mutations
99 I 5 14 19 0.770 0.592 View mutations
100 S 17 2 19 0.126 0.432 View mutations