O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
776 S 19 0 19 0.032 0.892 View mutations
777 A 19 0 19 0.036 0.903 View mutations
778 Q 16 3 19 0.168 0.689 View mutations
779 P 19 0 19 0.020 0.681 View mutations
780 C 19 0 19 0.000 0.641 View mutations
781 D 3 16 19 0.764 0.390 View mutations
782 S 18 1 19 0.053 0.491 View mutations
783 I 19 0 19 0.017 0.386 View mutations
784 V 10 9 19 0.490 0.500 View mutations
785 V 17 2 19 0.151 0.465 View mutations
786 A 0 19 19 0.975 0.584 View mutations
787 Y 0 19 19 0.989 0.564 View mutations
788 Y 3 16 19 0.885 0.568 View mutations
789 F 11 8 19 0.468 0.473 View mutations
790 C 18 1 19 0.043 0.341 View mutations
791 G 8 11 19 0.543 0.532 View mutations
792 E 4 15 19 0.748 0.626 View mutations
793 P 11 8 19 0.474 0.476 View mutations
794 I 16 3 19 0.171 0.330 View mutations
795 P 11 8 19 0.477 0.467 View mutations
796 Y 10 9 19 0.517 0.488 View mutations
797 R 3 16 19 0.862 0.587 View mutations
798 T 11 8 19 0.475 0.469 View mutations
799 L 8 11 19 0.569 0.517 View mutations
800 V 19 0 19 0.005 0.332 View mutations