O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 P 2 17 19 0.837 0.265 View mutations
277 A 18 1 19 0.067 0.773 View mutations
278 D 19 0 19 0.060 0.780 View mutations
279 D 6 13 19 0.641 0.369 View mutations
280 L 14 5 19 0.335 0.634 View mutations
281 S 6 13 19 0.646 0.345 View mutations
282 L 16 3 19 0.155 0.699 View mutations
283 S 14 5 19 0.304 0.684 View mutations
284 E 1 18 19 0.879 0.176 View mutations
285 G 9 10 19 0.540 0.467 View mutations
286 T 18 1 19 0.031 0.905 View mutations
287 S 18 1 19 0.057 0.883 View mutations
288 G 12 7 19 0.411 0.570 View mutations
289 S 19 0 19 0.030 0.842 View mutations
290 S 8 11 19 0.574 0.426 View mutations
291 C 6 13 19 0.643 0.356 View mutations
292 V 6 13 19 0.690 0.390 View mutations
293 I 19 0 19 0.038 0.610 View mutations
294 A 7 12 19 0.601 0.437 View mutations
295 A 18 1 19 0.049 0.431 View mutations
296 L 16 3 19 0.195 0.437 View mutations
297 G 2 17 19 0.886 0.439 View mutations
298 N 0 19 19 0.961 0.434 View mutations
299 T 1 18 19 0.943 0.431 View mutations
300 W 0 19 19 1.000 0.405 View mutations