O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 I 0 19 19 0.979 0.653 View mutations
252 P 0 19 19 1.000 0.742 View mutations
253 V 0 19 19 1.000 0.789 View mutations
254 I 3 16 19 0.839 0.639 View mutations
255 L 1 18 19 0.937 0.741 View mutations
256 T 0 19 19 0.993 0.787 View mutations
257 N 0 19 19 1.000 0.749 View mutations
258 Q 0 19 19 0.988 0.822 View mutations
259 I 3 16 19 0.810 0.663 View mutations
260 T 8 11 19 0.522 0.532 View mutations
261 T 1 18 19 0.932 0.579 View mutations
262 H 3 16 19 0.811 0.416 View mutations
263 L 5 14 19 0.747 0.427 View mutations
264 S 10 9 19 0.573 0.460 View mutations
265 G 19 0 19 0.022 0.782 View mutations
266 A 18 1 19 0.044 0.725 View mutations
267 L 9 10 19 0.533 0.460 View mutations
268 A 18 1 19 0.103 0.749 View mutations
269 S 14 5 19 0.197 0.639 View mutations
270 Q 17 2 19 0.172 0.813 View mutations
271 A 16 3 19 0.159 0.652 View mutations
272 D 19 0 19 0.007 0.778 View mutations
273 L 18 1 19 0.064 0.701 View mutations
274 V 9 10 19 0.506 0.457 View mutations
275 S 18 1 19 0.059 0.815 View mutations