O15524 (O15524)

Overview
Predicted structure (AF):
AF-O15524-F1-model_v4
Uniprot entry:
O15524
Gene:
O15524
Protein length:
211 residues
Mutations found:
4008
Benign based on D2Deep prediction:
3142 out of 4008 mutations
Pathogenic based on D2Deep prediction:
866 out of 4008 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4008 mutations across 211 unique positions. There are 3142 benign and 866 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 F 19 0 19 0.004 0.118 View mutations
102 L 17 2 19 0.134 0.234 View mutations
103 V 19 0 19 0.066 0.207 View mutations
104 R 12 7 19 0.422 0.392 View mutations
105 D 6 13 19 0.569 0.621 View mutations
106 S 1 18 19 0.894 0.807 View mutations
107 R 16 3 19 0.159 0.371 View mutations
108 Q 17 2 19 0.194 0.212 View mutations
109 R 19 0 19 0.041 0.307 View mutations
110 N 18 1 19 0.086 0.232 View mutations
111 C 19 0 19 0.090 0.291 View mutations
112 F 19 0 19 0.048 0.196 View mutations
113 F 17 2 19 0.106 0.279 View mutations
114 A 17 2 19 0.141 0.314 View mutations
115 L 18 1 19 0.186 0.239 View mutations
116 S 5 14 19 0.704 0.675 View mutations
117 V 6 13 19 0.656 0.607 View mutations
118 K 8 11 19 0.608 0.525 View mutations
119 M 7 12 19 0.565 0.540 View mutations
120 A 18 1 19 0.099 0.402 View mutations
121 S 5 14 19 0.699 0.569 View mutations
122 G 0 19 19 0.966 0.788 View mutations
123 P 1 18 19 0.882 0.749 View mutations
124 T 2 17 19 0.881 0.736 View mutations
125 S 1 18 19 0.933 0.782 View mutations