O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 D 3 16 19 0.823 0.569 View mutations
252 L 4 15 19 0.780 0.674 View mutations
253 D 1 18 19 0.947 0.723 View mutations
254 D 2 17 19 0.913 0.711 View mutations
255 L 5 14 19 0.735 0.635 View mutations
256 S 5 14 19 0.774 0.603 View mutations
257 L 0 19 19 0.969 0.770 View mutations
258 R 0 19 19 1.000 0.964 View mutations
259 T 4 15 19 0.802 0.725 View mutations
260 R 5 14 19 0.683 0.687 View mutations
261 L 0 19 19 0.989 0.782 View mutations
262 L 0 19 19 1.000 0.882 View mutations
263 N 5 14 19 0.713 0.628 View mutations
264 G 14 5 19 0.314 0.401 View mutations
265 L 13 6 19 0.353 0.436 View mutations
266 A 4 15 19 0.719 0.616 View mutations
267 Q 6 13 19 0.683 0.547 View mutations
268 Q 18 1 19 0.064 0.378 View mutations
269 M 2 17 19 0.804 0.554 View mutations
270 I 4 15 19 0.747 0.569 View mutations
271 S 17 2 19 0.156 0.482 View mutations
272 L 17 2 19 0.104 0.436 View mutations
273 A 4 15 19 0.722 0.596 View mutations
274 N 2 17 19 0.879 0.539 View mutations
275 N 18 1 19 0.066 0.497 View mutations