O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 L 18 1 19 0.121 0.392 View mutations
202 D 10 9 19 0.426 0.498 View mutations
203 N 15 4 19 0.177 0.399 View mutations
204 I 12 7 19 0.297 0.458 View mutations
205 L 6 13 19 0.686 0.568 View mutations
206 S 1 18 19 0.946 0.666 View mutations
207 H 5 14 19 0.735 0.509 View mutations
208 I 6 13 19 0.660 0.549 View mutations
209 Y 2 17 19 0.859 0.608 View mutations
210 Y 18 1 19 0.054 0.357 View mutations
211 F 3 16 19 0.790 0.613 View mutations
212 R 0 19 19 1.000 0.702 View mutations
213 C 0 19 19 1.000 0.791 View mutations
214 R 1 18 19 0.939 0.617 View mutations
215 D 3 16 19 0.854 0.663 View mutations
216 Y 0 19 19 0.996 0.645 View mutations
217 T 16 3 19 0.241 0.392 View mutations
218 E 1 18 19 0.935 0.695 View mutations
219 L 15 4 19 0.245 0.354 View mutations
220 L 18 1 19 0.189 0.311 View mutations
221 A 19 0 19 0.007 0.277 View mutations
222 Q 13 6 19 0.342 0.467 View mutations
223 V 19 0 19 0.026 0.388 View mutations
224 Y 14 5 19 0.266 0.494 View mutations
225 L 13 6 19 0.423 0.468 View mutations