O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 L 0 19 19 0.989 0.685 View mutations
227 P 19 0 19 0.001 0.352 View mutations
228 D 16 3 19 0.229 0.486 View mutations
229 F 0 19 19 1.000 0.592 View mutations
230 L 3 16 19 0.847 0.550 View mutations
231 S 18 1 19 0.061 0.417 View mutations
232 E 12 7 19 0.352 0.447 View mutations
233 H 0 19 19 1.000 0.563 View mutations
234 S 2 17 19 0.911 0.579 View mutations
235 K 15 4 19 0.247 0.483 View mutations
236 V 9 10 19 0.492 0.505 View mutations
237 R 3 16 19 0.866 0.571 View mutations
238 L 0 19 19 1.000 0.677 View mutations
239 V 1 18 19 0.932 0.642 View mutations
240 I 4 15 19 0.797 0.593 View mutations
241 V 4 15 19 0.795 0.620 View mutations
242 D 0 19 19 1.000 0.816 View mutations
243 G 5 14 19 0.694 0.603 View mutations
244 I 19 0 19 0.017 0.240 View mutations
245 A 5 14 19 0.698 0.670 View mutations
246 F 8 11 19 0.534 0.538 View mutations
247 P 18 1 19 0.067 0.287 View mutations
248 F 0 19 19 1.000 0.811 View mutations
249 R 11 8 19 0.444 0.443 View mutations
250 H 1 18 19 0.936 0.632 View mutations