O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 5 14 19 0.676 0.571 View mutations
127 P 0 19 19 1.000 0.992 View mutations
128 G 0 19 19 1.000 1.000 View mutations
129 V 1 18 19 0.948 0.788 View mutations
130 G 0 19 19 1.000 0.941 View mutations
131 K 0 19 19 1.000 0.883 View mutations
132 T 0 19 19 1.000 0.910 View mutations
133 Q 0 19 19 1.000 0.850 View mutations
134 L 0 19 19 0.999 0.792 View mutations
135 C 1 18 19 0.942 0.690 View mutations
136 M 2 17 19 0.881 0.642 View mutations
137 Q 0 19 19 1.000 0.802 View mutations
138 L 0 19 19 0.995 0.834 View mutations
139 A 12 7 19 0.329 0.443 View mutations
140 V 1 18 19 0.948 0.795 View mutations
141 D 0 19 19 1.000 0.871 View mutations
142 V 12 7 19 0.356 0.394 View mutations
143 Q 19 0 19 0.000 0.129 View mutations
144 I 19 0 19 0.050 0.244 View mutations
145 P 17 2 19 0.234 0.221 View mutations
146 E 19 0 19 0.003 0.415 View mutations
147 C 6 13 19 0.652 0.560 View mutations
148 F 17 2 19 0.127 0.330 View mutations
149 G 17 2 19 0.156 0.186 View mutations
150 G 15 4 19 0.268 0.295 View mutations