O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 C 8 11 19 0.590 0.526 View mutations
177 I 7 12 19 0.625 0.440 View mutations
178 Q 18 1 19 0.053 0.537 View mutations
179 H 7 12 19 0.658 0.516 View mutations
180 L 13 6 19 0.308 0.421 View mutations
181 Q 18 1 19 0.116 0.646 View mutations
182 L 18 1 19 0.074 0.530 View mutations
183 I 17 2 19 0.194 0.479 View mutations
184 A 17 2 19 0.124 0.624 View mutations
185 E 18 1 19 0.028 0.759 View mutations
186 K 19 0 19 0.007 0.795 View mutations
187 H 19 0 19 0.006 0.879 View mutations
188 K 19 0 19 0.000 0.963 View mutations
189 G 11 8 19 0.378 0.571 View mutations
190 E 19 0 19 0.012 0.808 View mutations
191 E 17 2 19 0.187 0.666 View mutations
192 H 19 0 19 0.038 0.849 View mutations
193 R 17 2 19 0.105 0.777 View mutations
194 K 13 6 19 0.311 0.583 View mutations
195 A 19 0 19 0.009 0.499 View mutations
196 L 19 0 19 0.013 0.569 View mutations
197 E 19 0 19 0.007 0.609 View mutations
198 D 17 2 19 0.127 0.516 View mutations
199 F 16 3 19 0.227 0.479 View mutations
200 T 5 14 19 0.694 0.434 View mutations