O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 V 15 4 19 0.298 0.421 View mutations
152 A 3 16 19 0.850 0.534 View mutations
153 G 11 8 19 0.427 0.469 View mutations
154 E 15 4 19 0.336 0.383 View mutations
155 A 7 12 19 0.618 0.527 View mutations
156 V 4 15 19 0.763 0.577 View mutations
157 F 7 12 19 0.657 0.587 View mutations
158 I 0 19 19 0.983 0.735 View mutations
159 D 0 19 19 1.000 0.860 View mutations
160 T 0 19 19 0.919 0.983 View mutations
161 E 1 18 19 0.902 0.829 View mutations
162 G 0 19 19 1.000 0.921 View mutations
163 S 0 19 19 0.999 0.989 View mutations
164 F 0 19 19 0.999 0.806 View mutations
165 M 12 7 19 0.388 0.466 View mutations
166 V 6 13 19 0.710 0.559 View mutations
167 D 18 1 19 0.134 0.417 View mutations
168 R 13 6 19 0.388 0.425 View mutations
169 V 17 2 19 0.133 0.371 View mutations
170 V 19 0 19 0.001 0.360 View mutations
171 D 7 12 19 0.634 0.509 View mutations
172 L 16 3 19 0.244 0.395 View mutations
173 A 19 0 19 0.002 0.307 View mutations
174 T 19 0 19 0.001 0.529 View mutations
175 A 11 8 19 0.437 0.487 View mutations